Water absorption by decellularized dermis

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Response of human chondrocytes and mesenchymal stromal cells to a decellularized human dermis

BACKGROUND Although progress has been made in the treatment of articular cartilage lesions, they are still a major challenge because current techniques do not provide satisfactory long-term outcomes. Tissue engineering and the use of functional biomaterials might be an alternative regenerative strategy and fulfill clinical needs. Decellularized extracellular matrices have generated interest as ...

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Collagenase production by human dermis in vitro.

Isolated human dermis has been shown to produce a specific collagenase in vitro. Enzyme activity becomes detectable after two days of culture, reaches a peak on the fourth day, and then begins to decline. Like collagenase obtained from cultures of whole human skin, dermal collagenase is inhibited by human serum and EDTA. The possible sources of this enzyme are discussed. Collagenolytic activity...

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ژورنال

عنوان ژورنال: Heliyon

سال: 2018

ISSN: 2405-8440

DOI: 10.1016/j.heliyon.2018.e00600